Controlling Intramolecular Interactions in the Design of Selective, High-Affinity, Ligands for the CREBBP Bromodomain
Michael Brand,James Clayton,Mustafa Moroglu,Matthias Schiedel,Sarah Picaud,Joseph P. Bluck,Anna Skwarska,Hannah Bolland,Anthony K. N. Chan,Corentine M. C. Laurin,Amy R. Scorah,Larissa See,Timothy P. C. Rooney,Katrina H. Andrews,Oleg Fedorov,Gabriella Perell,Prakriti Kalra, Kayla B. Vinh,Wilian A. Cortopassi,Pascal Heitel,Kirsten E. Christensen,Richard Cooper,Robert S. Paton,William C. K. Pomerantz,Philip C. Biggin,Ester M. Hammond,Panagis Filippakopoulos,Stuart J. Conway JOURNAL OF MEDICINAL CHEMISTRY(2021)
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