Poppers, by Inducing HHV-8 Virion Production, Can Act as a Promoter for HHV-8 Transmission in Men Who Have Sex With Men.

Aude Jary,Adélie Gothland,Romain Palich,Valentin Leducq,Gentiane Monsel,Sébastien Imbert,Luminita Schneider,Anne Simon,Jean-Philippe Spano,Christine Katlama,Islam Amine Larabi,Jean-Claude Alvarez,Vincent Calvez,Anne-Geneviève Marcelin

Open forum infectious diseases（2021）

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摘要

Environmental factors were reported to increase the risk of human herpesvirus 8 (HHV-8) transmission. In a population of men who have sex with men (MSM), we found evidence that chemsex was associated with human herpesvirus 8 seropositivity in vivo and that poppers induced HHV-8 virion production in vitro. Our finding may explain the higher HHV-8 transmission in MSM.

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关键词

HHV-8,HHV-8 production,HIV PrEP,MSM,chemsex,poppers

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