Clinical Impact of Heritable Thrombophilia on Neonatal-Onset Thromboembolism: A Nationwide Study in Japan
The Journal of Pediatrics(2021)
摘要
Monoallelic protein C-variants had a higher incidence of neonatal-thromboembolism than biallelic variants. Thrombophilia genetic testing should be performed in the setting of neonatal-thromboembolism and low protein C to identify the underlying genetic defect.
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关键词
protein C,protein S,antithrombin,purpura fulminans,newborn infants,thrombophilia
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