The effect of CYP2D6 and CYP2C9 gene polymorphisms on the efficacy and safety of the combination of tramadol and ketorolac used for postoperative pain management in patients after video laparoscopic cholecystectomy.
Drug metabolism and personalized therapy(2021)
Abstract
and can predict analgesic effectiveness of tramadol and ketorolac. can predict the risk of gastrointestinal bleeding, including those hidden to ketorolac.
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Key words
CYP2C9,CYP2D6,ketorolac,non-steroidal anti-inflammatory drugs (NSAIDs),pharmacogenetics,tramadol
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