Biomarkers of laryngeal squamous cell carcinoma: a review

Annals of Diagnostic Pathology(2021)

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摘要
Laryngeal carcinoma is the second common malignancy of the upper aerodigestive tract after lung cancer; in most cases is a squamous cell carcinoma, whose risk factors include tobacco smoking and alcohol consumption. Despite therapeutic progress, the five-year overall survival rate for this malignancy has remained nearly 50% and many patients already present metastasis at the time of diagnosis.
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关键词
Laryngeal neoplasms,RNA, long noncoding,Ki-67 antigen,Focal adhesion protein-tyrosine kinases,Cyclin D1,Tumour suppressor protein p53,Cadherins,Receptors, growth factor
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