Ageing mechanisms that contribute to tissue remodeling in lung disease
Ageing Research Reviews（2021）
Abstract
•Ageing leads to declines in lung health, function and resilience.•Ageing pre-disposes the lung for disrepair, increasing disease susceptibility.•Pathological remodeling, rather than wound repair is likely to follow injury.•IPF, COPD, ARDS and severe phenotypes of asthma are age-related lung diseases.•Ageing mechanisms are potential therapeutic targets for these diseases.
MoreTranslated text
Key words
Acute respiratory distress syndrome (ARDS),Chronic obstructive pulmonary disease (COPD),Damage associated molecular pattern (DAMP),Idiopathic pulmonary fibrosis (IPF),Immunosenescence,Mitochondrial dysfunction
AI Read Science
Must-Reading Tree
Example
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined