Post-Corona-Virus-Disease-19 Arthritis. Manifestation Under The Clinical Picture Of A Reactive Arthritis

A total of 13 case reports of reactive arthritis reported in the literature in connection with coronavirus disease 2019 (COVID-19) are reviewed. Men were affected more frequently than women. The arthritis was manifested 4-44 days after the infection or the occurrence of the COVID-19 symptoms. Acute arthritis was monoarticular or oligoarticular. Only 1 out of 7 patients examined was human-leucocyte-antigen(HLA)-B27 positive. A direct viral infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could not be detected in the synovial fluid and was not investigated in the synovial membrane. The arthritis was successfully treated with nonsteroidal anti-inflammatory drugs and/or intra-articular or systemic corticosteroids. The pathogenesis of post-COVID-19 reactive arthritis is unknown.