Subdiffusion equation with Caputo fractional derivative with respect to another function in modeling diffusion in a complex system consisting of a matrix and channels.

Anomalous diffusion of an antibiotic (colistin) in a system consisting of packed gel (alginate) beads immersed in water is studied experimentally and theoretically. The experimental studies are performed using the interferometric method of measuring concentration profiles of a diffusing substance. We use the g-subdiffusion equation with the fractional Caputo time derivative with respect to another function g to describe the process. The function g and relevant parameters define anomalous diffusion. We show that experimentally measured time evolution of the amount of antibiotic released from the system determines the function g. The process can be interpreted as subdiffusion in which the subdiffusion parameter (exponent) α decreases over time. The g-subdiffusion equation, which is more general than the "ordinary" fractional subdiffusion equation, can be widely used in various fields of science to model diffusion in a system in which parameters, and even a type of diffusion, evolve over time. We postulate that diffusion in a system composed of channels and a matrix can be described by the g-subdiffusion equation, just like diffusion in a system of packed gel beads placed in water.