Genes Relevant to Tissue Response to Cancer Therapy Display Diurnal Variation in mRNA Expression in Human Oral Mucosa.

Fangyi Gu,Eduardo Cortes Gomez,Jianhong Chen,Matthew F Buas,Nicolas F Schlecht,Karen Hulme, Shweta Vishwas Kulkarni,Prashant K Singh, Richard O'Connor,Christine B Ambrosone,Anurag K Singh,Jianmin Wang

Journal of circadian rhythms（2021）

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摘要

In oral mucosa, expression of some genes relevant to treatment response displayed diurnal variation. These genes may be candidates for development of biomarkers for optimizing individual timing of cancer therapy using non-invasively collected oral mucosa.

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关键词

biomarkers,cancer therapy,chronotherapy,circadian rhythm,oral mucosa

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