Association between accelerometer-measured physical activity, glucose metabolism, and waist circumference in older adults.

AIMS:To examine the association of physical activity (PA) and sedentary time (ST) with glucose metabolism according to waist circumference (WC) in older people. METHODS:A population-based sample of 702 individuals (aged 67-70 years) wore wrist-worn accelerometers for two weeks and underwent an oral glucose tolerance test. The associations between moderate-to-vigorous (MVPA) and light (LPA) PA, ST, and glucose metabolism across the tertiles of WC were analysed using general linear regression. RESULTS:Among highest WC tertile, LPA negatively associated with fasting insulin (β =  - 0.047, 95% CI - 0.082 to - 0.012), HOMA-IR (β =  - 0.098, 95% CI - 0.184 to - 0.012), and HOMA-β (β =  - 3.367, CI - 6.570 to - 0.783). ST associated with 120 min glucose (β = 0.140, CI 0.021 to 0.260). Among lowest WC tertile, MVPA negatively associated with 30 min insulin (β =  - 0.086, 95% CI - 0.168 to - 0.004) and 120 min insulin (β =  - 0.160, 95% CI - 0.257 to - 0.063) and positively associated with Matsuda index (β = 0.076, 95% CI 0.014 to 0.139). Light PA negatively associated with 120 min insulin (β =  - 0.054, 95% CI - 0.104 to - 0.005). CONCLUSION:With the limitation of the cross-sectional study, reducing ST and increasing LPA may be beneficial for glucose metabolism among abdominally obese older adults. Lean older adults could benefit more from increasing MVPA.