Structural characterization and immunomodulatory activity of a glucan from Radix Codonopsis

•CPC was an α-glucan isolated from the roots of Codonopsis pilosula.•The structure of CPC exhibited the backbone of 1,4-linked α-D-glucose and the branched chains of 1,6-linked β-D-glucose.•CPC exhibited the potential of immunomodulatory activity on RAW264.7 cells.