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RUNX1 gene alterations characterized by allelic preference in adult acute myeloid leukemia

Cosimo Cumbo, Giuseppina Tota, Anna De Grassi, Luisa Anelli, Antonella Zagaria, Nicoletta Coccaro, Francesco Tarantini, Crescenzio Francesco Minervini, Elisa Parciante, Luciana Impera, Maria Rosa Conserva, Immacolata Redavid, Anna Mestice, Immacolata Attolico, Ciro Leonardo Pierri, Pellegrino Musto, Francesco Albano

Leukemia & lymphoma（2023）

Cited 4|Views29
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Abstract
Germline mutations in the RUNX1 gene define a familial platelet disorder with a predisposition to myeloid malignancy (FPDMM). This autosomal dominant disorder is characterized by variable penetranc...
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