First Experience Addressing the Prognostic Utility of Novel Urinary Biomarkers in Patients with COVID-19

Open forum infectious diseases(2021)

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摘要
Urine 11-dehydro-thromboxane B (u11-dh-TxB), 8-hydroxy-2'-deoxyguanosine (8-OHdG), and liver-type fatty acid binding protein levels (L-FABP) at the time of hospitalization were higher in coronavirus disease 2019 (COVID-19) patients with adverse events vs without events. Higher u11-dh-TxB and L-FABP levels were associated with longer hospitalization, more thrombotic events, and greater mortality, providing evidence for potential utility as early prognostic biomarkers for COVID-19.
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关键词
COVID-19,liver-type fatty acid binding protein,urinary 11-dehydro- thromboxane B2,urinary 8-hydroxy-2’-deoxyguanosine
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