Influence Of Daily Aspirin Therapy On Ace2 Expression And Function-Implications For Sars-Cov-2 And Patients With Aspirin-Exacerbated Respiratory Disease

CLINICAL AND EXPERIMENTAL ALLERGY(2021)

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摘要
In March 2020, the French Minister of Health warned against the use of non-steroidal anti-inflammatory drugs (NSAIDs) like aspirin and ibuprofen, suggesting that their use might be associated with more severe disease presentation in patients with COVID-19.1 This advice was apparently based on unpublished anecdotal reports that patients who had been exposed to NSAIDs developed more severe symptoms of COVID-19.
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关键词
ACE2, Aspirin, aspirin-exacerbated respiratory disease, asthma, COVID-19, NSAID, SARS-CoV-2, TMPRSS2
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