Aspilia africana C. D. Adams inhibits the production of lipopolysaccharide-induced inflammatory mediators in murine macrophage RAW264.7 cells by suppressing the NF-κB and PI3K/Akt pathways

Irvine Niyonizigiye,Daniel Ngabire,David Nkurunziza,Maheshkumar Prakash Patil,Alka Ashok Singh,Jérémie Ngezahayo,Gun-Do Kim

SOUTH AFRICAN JOURNAL OF BOTANY（2021）

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摘要

•Anti-inflammatory effects of Aspilia africana C. D. Adams (A. africana) in RAW264.7 cells stimulated with Lipopolysaccharide were investigated.•A. africana inhibited the production of nitric oxide (NO).•A. africana inhibited the activation of NF-κB and PI3K/Akt signaling pathways.

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关键词

Aspilia africana,Lipopolysaccharide,RAW264.7 cells,Inflammation,Nitric oxide

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