Biochanin A protects SH-SY5Y cells against isoflurane-induced neurotoxicity by suppressing oxidative stress and apoptosis

Qiaoling Wu,You Shang,Tu Shen,Feifei Liu, Wei Zhang

NeuroToxicology（2021）

引用 6|浏览5

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摘要

•BCA suppresses isoflurane-induced viability reduction, oxidative stress, and apoptosis in SH-SY5Y cells.•BCA enhances isoflurane-induced activation of Nrf2/ARE pathway.•Knockdown of Nrf2 inhibits BCA protection against isoflurane-induced neurotoxicity.

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关键词

Biochanin A,SH-SY5Y cells,Isoflurane,Apoptosis,Oxidative stress,Nrf2/ARE pathway

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