In vitro hazard characterization of simulated aircraft cabin bleed-air contamination in lung models using an air-liquid interface (ALI) exposure system

Rui-Wen He,Marc M G Houtzager,W P Jongeneel,Remco H S Westerink,Flemming R Cassee

Environment International（2021）

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摘要

•“Mini-BACS + AES” setup can be used for in vitro hazard characterization of simulated fume events.•Aircraft hydraulic fluid fumes are more harmful than engine oil fumes.•Higher OP level and smaller particle size may contribute to higher toxicity of hydraulic fluid fumes.•Our results clearly reflect potential health risks associated with fume events in aircraft cabins.

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关键词

Fume event,Aircraft cabin air,Mini-BACS,Organophosphates,Co-culture,BMD analysis

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