Predictors for quality of life among older adults with depressive disorders: A prospective 3-month follow-up cohort study

Purpose The study aimed to investigate the predictive factors for quality of life among subjects with late-life depression. Design and Methods Data including depressive symptoms assessed by the Hamilton Rating Scale of Depression (HAMD), geriatric depression scale (GDS), perceived stress scale (PSS), multidimensional scale for perceived social support, and the EQ-5D scale were collected at baseline and at 3-month follow-up from 264 participants. Findings After controlling for covariates, time, GDS, PSS, HAMD, and living alone were confirmed predictors for change of EQ-5D scores. Practice Implications Perceived stress is important, and intervention to reduce stress especially in early treatment of depressive disorder should be encouraged.