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Tumor-Like Lesions In Patients With Granulomatosis With Polyangiitis: A Case Series

ISRAEL MEDICAL ASSOCIATION JOURNAL(2021)

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摘要
Background: Granulomatosis with potyangiitis (GPA) is a rare small vessel vascutitis. It usually involves the respiratory tract and kidneys. Rarely, tumor-resembling inflammatory changes ensue.Objectives: To report three unique cases of GPA presenting with tumor-like lesions in various organs.Methods: We presented three cases of GPA. Case 1 presented with typical upper respiratory symptoms of GPA and a mediastinal mass. Case 2 presented with low back pain, a large retroperitoneat mass, and nodular skin lesions. Case 3 presented with epigastric pain and a paravertebral inflammatory mass.Results: The patients were treated successfully with rituximab.Conclusions: Clinicians should be aware of this presentation of granulomatosis with polyangiitis, which is known as Tumefaction Wegener's granulomatosis.
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granutomatosis with polyangiitis, inflammation, tumor lesions, vasculitis
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