Structure, Interdomain Dynamics, and Ph-Dependent Autoactivation of Pro-Rhodesain, the Main Lysosomal Cysteine Protease from African Trypanosomes
JOURNAL OF BIOLOGICAL CHEMISTRY(2021)
关键词
proenzyme,zymogen,cysteine protease,rhodesain,autoinhibition,fluorescence correlation spectroscopy (FCS),molecular dynamics,crystal structure,Trypanosoma brucei,African Sleeping Sickness
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