A Volume Source Method for Solving ECGI Inverse Problem.

Electrocardiographic Imaging (ECGI) is a non-invasive procedure that allows to reconstruct the electrical activity of the heart from body surface potential map (BSPM). In this paper, we present a volume model to solve the electrocardiography inverse problem capable to take into account structural informations obtained by imaging techniques. Thedirect problem maps a volume current in the cardiac muscle (ventricles) to the body surface electrical measures. The model is based on coupling bidomain heart model with torso conduction. The corresponding inverse problem is solved with the Tikhonov regularization. Simulated database are used for the evaluation of this method and we compared them to standard method of fundamental solutions (MFS). The sensitivity to noise is also assessed. The correlation coefficients (CC) and the relative error (RE) of activation times were computed. Results show that the CC (respectively RE) median is respectively 0.75 for the volume model and 0.4 for the MFS (respectively 0.31 vs 0.35) on the epicardium. On the endocardium, the CC and the RE median are 0.65 and 0.33 for the volume method. In conclusion, the volume method performs better than the method of fundamental solutions (MFS) for any noise level, and reconstruct in addition endocardial information.