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Prospective prediction of clinical drug response in high-grade gliomas using an ex vivo 3D cell culture assay.

Stephen Shuford,Lindsay Lipinski,Ajay Abad,Ashley M Smith,Melissa Rayner,Lauren O'Donnell,Jeremy Stuart,Laszlo L Mechtler,Andrew J Fabiano,Jeff Edenfield,Charles Kanos,Stephen Gardner,Philip Hodge,Michael Lynn,Nicholas A Butowski,Seunggu J Han,Navid Redjal,Howland E Crosswell,Cecile Rose T Vibat,Lillia Holmes,Matthew Gevaert,Robert A Fenstermaker,Teresa M DesRochers

Neuro-oncology advances（2021）

Cited 13|Views7
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Abstract
This study both validates the developed assay analytically and clinically and provides case studies of its implementation in clinical practice.
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Key words
3D culture,drug response prediction,ex vivo,glioblastoma,glioma
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