THE EFFECTS OF ETANERCEPT AND CABERGOLINE ON ENDOMETRIOTIC IMPLANTS, UTERUS AND OVARIES IN RAT ENDOMETRIOSIS MODEL

Cihan Deniz Keleş,Birol Vural,Serdar Filiz,Fisun Vural,Gülçin Gacar,Fatma Ceyla Eraldemir,Sema Kurnaz

Journal of Reproductive Immunology（2021）

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Abstract

•Etanercept and/or cabergoline decreased volume of ectopic endometrial implants.•Etanercept and/or cabergoline decreased TNF-α and VEGF staining of ectopic endometrial implants.•Etanercept and/or Cabergoline decreased endometrial MSC-like cells of ectopic implants.•Etanercept and Etanercept + Cabergoline decreased TNF-α staining of the ovaries.•Etanercept + Cabergoline treatment increased peripheral blood CD25+ & CD5+ Cells.

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Key words

AFC,AMH,Cb,CD2,CD4,CD5,CD8a,CD25,CD45,CD146,Co,DRD2-A,E,ELISA,FITC,H&E,IHC,IL-6,IL-10,IL-13,IL-37,mTOR,NGF,PDGFR-Rβ,PE,PTPRC,Sh,TNF-α,Treg,VEGF

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