Knocking out c-Jun promotes cardiomyocyte differentiation from embryonic stem cells.

Lide Su,Guofu Zhang, Hui Zhong,Ling Luo,Yan Li, Chao Chi,LiLi Jiang,Ping Huang,Guihuan Liu,Ping Zhu,Kai Kang

International journal of cardiology（2021）

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摘要

Knocking out c-Jun directs ESCs towards a meso-endodermal cell lineage fate, in turn leading to generation of beating myocardial cells. Thus, c-Jun plays an important role in regulating early cardiac cell development.

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关键词

C-Jun,Cardiac differentiation,Embryonic body,Endoderm,Mesoderm

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