Evaluation of arsenic species in leukocytes and granulocytes of acute promyelocytic leukemia patients treated with arsenic trioxide

Journal of Pharmaceutical and Biomedical Analysis(2021)

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Abstract
•A HPLC-ICP-MS method was developed for intracellular arsenic speciation.•Arsenic species in leukocyte and granulocyte were analyzed for the first time.•Distribution trend of arsenic species in leukocytes and granulocytes was clarified.
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Key words
Acute promyelocytic leukemia,Arsenic species,Leukocyte,Granulocyte,HPLC-ICP-MS
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