Roles of Aryl-hydrocarbon Receptor in metabolism and proliferative behaviors of Bone Marrow MSCs: Implications for targeted therapy.

Yan Jia,Youshan Zhao,Zheng Zhang,Lei Shi,Ying Fang,Dong Wu,Lingyun Wu,Chunkang Chang

Current topics in medicinal chemistry（2021）

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摘要

Taken together, these findings demonstrated that activation of AHR signaling pathway reshaped the metabolism in BMMSCs and consequently inhibited their proliferation.

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关键词

Bone marrow mesenchymal stromal cells (BMMSCs),aryl-hydrocarbon receptor (AHR),metabolism,microenvironment,mitochondria,proliferation.

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