Aromatase And The Three Little Paralogs

The rapid progress of scientific knowledge is continuously built on established earlier findings. Integrating previous observations with more recent data can be challenging and occasionally well-established data is unfortunately overlooked. This may lead to unnecessary redundancy in research and, in the worst-case scenario, to misinterpretation of data. In the present contribution we would like to draw attention to such a circumstance, which has crept into several recent papers on expression and functional relevance of the porcine CYP19 gene cluster that encodes functionally distinct isoforms of aromatase cytochrome P450 (aromatase) in pigs.