Associations between neurofilament light chain levels, disease activity and brain atrophy in progressive multiple sclerosis.

Jarmila Szilasiova,Pavol Mikula,Jaroslav Rosenberger,Miriam Fedicova,Peter Urban,Lydia Frigova,Marianna Vitkova,Zuzana Gdovinova,Jozef Hanes,Eva Stevens

Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia（2022）

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摘要

The results show that pNfL levels are a useful biomarker of disease activity determined by NEDA-3 status, including brain MRI-volumetry, in patients with the progressive form of MS.

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关键词

brain volume loss,multiple sclerosis,neurofilament light chain,no evident disease activity,progressive MS

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