Pharmacogene Variation Consortium: A Global Resource And Repository For Pharmacogene Variation

The Pharmacogene Variation Consortium (PharmVar) was founded in 2017 to provide the clinical and research communities a repository and standardized nomenclature of genes contributing to variability in drug metabolism and response. Over the past 4 years, PharmVar has provided the research and clinical pharmacogenetics/genomics communities with essential information for flagship pharmacogenes with well-established drug-gene relationships and published clinical guidelines such as CYP2C9, CYP2C19, and CYP2D6. In this Perspective we highlight recent milestones and standardization efforts.