Phylodynamic analysis reveals changing transmission dynamics of HIV-1 CRF01_AE in Japan from heterosexuals to men who have sex with men

Machiko Otani,Teiichiro Shiino,Makiko Kondo,Atsuko Hachiya,Masako Nishizawa,Tadashi Kikuchi,Tetsuro Matano

International Journal of Infectious Diseases（2021）

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摘要

•CRF01_AE began to spread among MSM, with frequent cluster formations, in the 2000s.•CRF01_AE transmission risk has shifted from heterosexuals/IDUs to MSM since 2014.•Nevertheless, CRF01_AE transmissions among heterosexuals and IDUs have persisted.•Prevention measures need to target CRF01_AE in various populations in Japan.

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关键词

HIV-1,AIDS,Men who have sex with men,Molecular epidemiology,Cluster analysis,Japan

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