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Resting State Functional Connectivity And Relapse In Psychotic Depression

Nicholas Neufeld,George Alexopoulos,Erin Dickie,Jerrold Jeyachandra,Benoit Mulsant,Ellen Whyte,Samprit Banerjee,Barnett Meyers,Matthew Hoptman,Anthony Rothschild,Alastair Flint,Aristotle Voineskos

BIOLOGICAL PSYCHIATRY（2021）

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Abstract
Psychotic depression is a severe mental disorder with a high risk of relapse. Relapse prevention is therefore crucial and neuroimaging biomarkers may prove useful in predicting relapse. Our group recently demonstrated that thinner cortex in an insular-limbic (IL) network was related to treatment outcome. We sought to examine resting state functional connectivity (rsFC) from this IL network to determine associations with relapse.
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Key words
Psychotic Depression, Resting State Functional Connectivity, Relapse, Biomarkers
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