Abstract 15227: Egln1 Deficiency Induce Alveolar Macrophages Accumulation and Polarize Lung Interstitial Macrophages to a Pro-pah State Mediating Obliterative Pulmonary Vascular Remodeling and Severe PAH
Circulation(2020)
摘要
Introduction: Previously we identified a mouse model (Tie2Cre-mediated disruption of Egln1) of Pulmonary arterial hypertension (PAH) with progressive obliterative vascular remodeling including vasc...
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