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Cistanche deserticola polysaccharide inhibits OVX-induced bone loss in mice and RANKL-induced osteoclastogenesis

Wen Xiao,Yanyan Wei,Fang Yang,Xiangyi Lu,Shuowen Liu,Yongling Long,Yang Yu

Journal of Functional Foods（2021）

Cited 7|Views5
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Abstract
•Active CDP was isolated and purified from Cistanche deserticola.•An osteoporosis mouse model was successfully constructed through ovariectomy.•CDP can effectively inhibit osteoclast formation and OVX-induced bone loss.•CDP is a potentially safe and effective drug for the treatment of osteoporosis.
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Key words
Osteoporosis,Cistanche deserticola polysaccharide,Ovariectomy,Osteoclast
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