Recurrence of previous chilblain lesions during the second wave of COVID-19: can we still doubt the correlation with SARS-CoV-2?

Between March and April 2020, after the onset of the first wave of the COVID-19 pandemic, a cluster of acral chilblain-like lesions (ACBLL) was observed in young subjects. Despite efforts to substantiate the correlation of ACBLL with SARS-CoV-2 infection, only a minority of cases have tested positive on reverse transcriptase polymerase chain reaction (RT-PCR) or serology. Only 3 of the 33 patients with ACBLL seen at our hospital in this period had evidence of recent SARS-CoV-2 infection on these tests.