Cutaneous Manifestations of Diabetes

Diabetes mellitus (DM) is a significant worldwide health concern with an estimated global prevalence of 9.3% in 2019.1 Global incidence has more than doubled since 1990 and is projected to continue increasing in the future.2 DM is more prevalent in high-income countries, and the projected prevalence in the United States by 2050 is 21% to 33%.3 Diabetes negatively impacts quality of life and is associated with a two- to three-fold increase in all-cause mortality.2 Type 2 DM (T2DM) accounts for approximately 90% of all diabetes.1 Cutaneous manifestations of DM are common and have been reported in 30% to 79% of patients with diabetes.4,5 The spectrum of DM-associated cutaneous disease is vast, and ranges from benign to life-threatening conditions (Table 1). Even "benign"