Development of unenhanced CT-based imaging signature for BAP1 mutation status prediction in malignant pleural mesothelioma: Consideration of 2D and 3D segmentation

Xiao-Jie Xie,Si-Yun Liu,Jian-You Chen,Yi Zhao,Jie Jiang,Li Wu,Xing-Wen Zhang, Yi Wu,Hui Duan, Bing He,Heng Luo,Dan Han

Lung Cancer（2021）

Cited 9|Views7

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Abstract

•CT-based 3D radiomics is superior to 2D for predicting BAP1 mutation status in malignant pleural mesothelioma.•3D radiomic features have better repeatability than 2D on malignant pleural mesothelioma research.•Clinical factors have no correlation with BAP1 mutation status in malignant pleural mesothelioma.

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Key words

AIC,ASCO,AUC,BAP1,ccRCC,CT,DCA,GLCM,GLDM,GLRLM,GLSZM,ICC,LASSO,LBP,LoG,LR,MPM,mRMR,N/A,NGTDM,NPV,PCR,“pe”,PPV,Radscore,ROC,ROI,SMOTE,2D,3D,WHO,Wav

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