Effectiveness and Tolerability of First-Line Afatinib for Advanced EGFR-Mutant Non-Small Cell Lung Cancer in Vietnam.

Thanh Ha Vu,Hoa Thi Thai Nguyen, Linh Khanh Dao, Chi Khanh Duong, Cao Van Nguyen, Tuyet Thi Doan,Hang Thi Thuy Nguyen, Hung Huy Hoang, Dung Khac Dinh, Giang Vinh Le, Thanh Thi Vu,Minh Cong Truong,Long Thanh Nguyen

Asian Pacific journal of cancer prevention : APJCP（2021）

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Abstract

First-line afatinib is beneficial for Vietnamese patients with advanced EGFR-mutant NSCLC with a good response rate and prolonged TTF with manageable adverse event profile. Baseline brain metastasis status and starting doses do not significantly impact TTF.
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Key words

EGFR mutation,advanced stage,non small cell lung cancer (NSCLC),real-world,second generation EGFR TKI

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