Synthesis Of Isoquinolones By Sequential Suzuki Coupling Of 2-Halobenzonitriles With Vinyl Boronate Followed By Cyclization

Saul Jaime-Figueroa,Michael J Bond, J Ignacio Vergara, Jake C Swartzel,Craig M Crews

JOURNAL OF ORGANIC CHEMISTRY（2021）

引用 3|浏览4

暂无评分

摘要

A novel, facile, and expeditious two-step synthesis of 3,4-unsubstituted isoquinolin-1(2H)-ones from a Suzuki cross-coupling between 2-halobenzonitriles and commercially available vinyl boronates followed by platinum-catalyzed nitrile hydrolysis and cyclization is described.

查看译文

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要