Genomic survey of SARS-CoV-2 vaccine breakthrough infections in healthcare workers from Kerala, India
The Journal of infection(2021)
Abstract
We describe genomic analysis of SARS-CoV-2 isolates from breakthrough infections in six healthcare workers following vaccination with AZD1222/Covishield. Four patients were infected by the variant of concern B.1.1.7 while other isolates possessed E484K and S477N mutations in spike protein associated with immune escape.
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