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A novel form of anti-angiogenic molecular antibody drug induces apoptosis in myeloma cells after cultivation upon endothelial feeder cells

Yavar Yousefi,Zohreh Mortezania, Mojdeh Abolmolouki,Amin Daemi

Leukemia Research（2021）

Cited 1|Views0
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Abstract
•Bevacizumab chitosan nanoparticle (BCSs) suppressed the VEGF factor.•BCSs disturbed the interconnections of myeloma cells and HUVECs as supportive cells.•BCSs increased the p53 expression in myeloma cells co-cultured with HUVECs.
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Key words
Myeloma,Bevacizumab,Nanoparticles-loaded CS
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