Mimics Of Malignancy Caused By Concurrent Imperforate Hymen And Transverse Vaginal Septum: An Instructive Case And Review Of The Literature

Ying-Fu Wang, Shih-Ming Kuo,Yu-Chun Lin, Hong-Hsiang Fang,Chun-Hao Chu,Chien-Ming Lin

JOURNAL OF INTERNATIONAL MEDICAL RESEARCH(2021)

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Abstract
The coexistence of imperforate hymen and vaginal septum is rare and their ability to mimic malignant manifestations have not been frequently reported. This current case report describes a 13-year-old girl that presented with cyclic abdominal pain for 6 months. She was found to have a huge mass via abdominal plain film X-ray and sonography, with inexplicably high levels of serum carcinoembryonic antigen, cancer antigen (CA)-19-9 and CA-125. Pelvic computed tomography imaging disclosed two huge cystic lesions in the uterine and upper vaginal cavities. Surgical intervention conformed the diagnosis of a concurrent imperforate hymen and transverse vaginal septum, echoing the imaging findings of haematocolpometra. Her tumour marker levels gradually returned to normal after surgery. This rare case of concomitant imperforate hymen and transverse vaginal septum highlights that haematocolpometra, a benign disease that might mimic malignancy, should be taken into consideration in any adolescent females with an abdominal mass and amenorrhoea to ensure an early diagnosis and timely appropriate management.
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Key words
Haematocolpos, haematometra, imperforate hymen, neoplasms, primary amenorrhoea, transverse vaginal septum, tumour markers
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