Association of obstructive sleep apnea with cognitive decline and age among non-demented older adults

Tengwei Pan,Suzhi Liu,Shaofa Ke,En Wang,Yiqing Jiang,Shanshan Wang

Neuroscience Letters（2021）

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摘要

•The OSA + group demonstrated a significant cognitive decline versus the OSA- group among non-demented individuals.•In APOE ε4- group, our findings showed a significant OSA * age interaction for immediate recall of ADAS-cog11 and RVALT, but not MMSE.•No significant interaction that was observed in the APOE ε4+ individuals.

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关键词

Sleep apnea,Age,Cognition,APOE ε4,Alzheimer’s disease

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