New Secodaphnane-Type Alkaloids with Cytotoxic Activities from Daphniphyllum angustifolium Hutch
NATURAL PRODUCTS AND BIOPROSPECTING(2021)
摘要
One new Daphniphyllum alkaloid, daphnioldhanol A ( 1 ), together with three known ones, were isolated from the stem part of Daphniphyllum angustifolium Hutch. Their structures were elucidated by spectroscopic methods and comparing with the literature data. Compound 2 is a new natural product, but known by synthesis as a racemate. Compound 1 exhibited week cytotoxic activity against Hela cell line with IC 50 of 31.9 μM. Graphic Abstract
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关键词
Daphniphyllum angustifolium hutch, Secodaphnane-type, Daphnioldhanol A, Cytotoxic activity
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