Immune and barrier characterization of atopic dermatitis skin phenotype in Tanzanian patients
Annals of Allergy, Asthma & Immunology(2021)
Abstract
The skin phenotype of Tanzanian AD patients is consistent with that of African-Americans, exhibiting dominant Th2/Th22-skewing, minimal dysregulation of terminal differentiation, and even broader attenuation of lipid metabolism-related products. These data highlight the unique characteristic of AD in black individuals, as well as the need to develop unique treatments targeting AD patients of these under-represented populations.
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Key words
African patients,Atopic dermatitis,T cell,Th2,barrier,biomarkers,clinical immunology,dermatology
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