Two New Terpenoids from Valeriana officinalis

AIM:To study the chemical constituents of the roots of Valeriana officinalis L.METHODS:Chemical constituents were isolated by various column chromatographic techniques and their structures were elucidated by spectroscopic methods.RESULTS:A new sesquiterpene, orivalerianol(4β, 10α, 15-trihydroxy-aromadrendane)(1), and a new iridoid, monovalerianester A(aglycone of kanokoside A)(2) together with eight known compounds rulepidol(3), behenic acid(4), pinoresinol(5), valerenic acid(6), β-sitosterol(7) , kanokoside A(8), prinsepiol-4-O-β-D-glucoside(9) and 8-hydroxypinoresinol-4-O-β-D-glucoside(10) were obtained from the EtOAc extract(1～6) and n-BuOH extract(7～10).CONCLUSION:Compounds 1 and 2 are new natural products.