Role of RIP1 in programmed cell death

International Journal of Pathology and Clinical Medicine（2013）

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摘要

Recent studies showed that RIP kinase functions as the crossroads for cell survival, death, apoptosis and necroptosis. Receptor interacting protein 1(RIP1), the irst member of the RIP family, plays a key role in regulation of cell signaling transduction. It is important to elucidate the structure, biological function and the role of RIP1 in programmed cell death.

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