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Eco-Friendly Construction Of Spiroquinazolin-2-(Thi)Ones And Quinolin-(Thio)Ureas Via Fe(Iii)-Catalyzed Multi-Component Domino Double [4+2] Annulations

Zhentao Pan,Shuaijun Shi,Xuancheng Yang,Xu-Qiong Xiao,Wangqin Zhang,Shiliang Wang,Yongmin Ma

GREEN CHEMISTRY（2021）

Cited 17|Views2
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Abstract
An unprecedented eco-friendly multi-component domino approach for the synthesis of novel spiroquinazolin-2-(thi)ones and quinolin-(thio)ureas is described. The protocol proceeds via domino double [4 + 2] annulations and features an eco-benign catalyst and solvent, simple starting materials, high atom-economy, H2O as the sole by-product and a simple work-up procedure.
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eco-friendly,multi-component
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