Design and evaluation of a 3D multi-manifold micromixer realized by a double-Archimedes-screw for rapid mixing within a short distance

•A single micromixer composed of double Archimedes-screw adapted to fit in microchannel to generate 3D omnidirectional momentum-changes and multiple jets for enhancing mixing performance.•With the spiral conformation, the Archimedes-screw micromixer (ASM) can substantially enhance fluid circulation.•The screw-turn of the ASM was investigated for an optimal design. The quantitative analysis of experimental mixing result shows good agreement with the simulation findings