Stability study of doripenem antibiotic applying LC-ESI-Q-TOF method and in silico prediction: An analytical investigation focused on degradation products

Fábio de Souza Barbosa,Leonardo Capra Pezzi,Fávero Reisdorfer Paula,Sarah Eller,Elfrides E.S. Schapoval,Tiago Franco de Oliveira,Andreas S.L. Mendez

Microchemical Journal（2021）

引用 1|浏览9

暂无评分

摘要

•A method by LC-ESI-QTOF for analysis of doripenem in infusion fluids was validated.•Stability after reconstitution and degradation products in clinical use conditions.•In silico prediction of products and degradation pathways using the Zeneth 7.•Characterization of degradation products formed under different stress conditions.

查看译文

关键词

Doripenem,Stability,Degradation products,In silico prediction,LC-ESI-Q-TOF

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要