Mesomics Project: Molecular Characterization Of Malignant Pleural Mesothelioma Using A Multi-Omic Approach
Journal of Thoracic Oncology(2021)
Abstract
The MESOMICS project for the multi-omic characterization of Malignant Pleural Mesothelioma (MPM) belongs to the Rare Cancers Genomics initiative (www.rarecancersgenomics.com) aiming at providing a better understanding of the molecular characteristics of rare cancers, such as MPM. Taking advantage of the expertise provided by a multidisciplinary team, and by means of state-of-the-art computational analyses as well as exceptional bio-repositories, our research is focused on: (1) identifying the molecular characteristics that may inform the carcinogenesis and aetiology of MPM; (2) providing the necessary data to generate a more clinically relevant classification of tumours; and (3) improving clinical management by identifying and validating novel candidate diagnostic, prognostic, and predictive biomarkers.
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Key words
Rare Cancers Genomics initiative, intra-tumor heterogeneity, genomics
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